A new substance prevents vascular calcification

The calcification of blood vessels and other soft tissues is problematic. Researchers at ETH Zurich and ETH spin-​off Inositec have discovered a substance that prevents vascular calcification.

by Anastasia Spyrogianni Roveri

Researchers at ETH Zurich and ETH spin-​off Inositec have developed a new substance to prevent vascular calcification, which affects many patients suffering from chronic kidney disease. As their metabolism is impaired, calcium salts may deposit in soft tissues, such as blood vessels or even the heart valves, causing them to stiffen. This often leads to severe, potentially fatal cardiovascular diseases. However, before patients can benefit from the substance further research and tests must be carried out.

“Calcification occurs when calcium phosphate crystals are deposited in tissue,” explains Jean-​Christophe Leroux, Professor of Drug Formulation and Delivery at ETH Zurich. “The compound adheres to calcium phosphate crystals, inhibiting their growth.”

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